Autopsy, histopathology and nano technological study of the spleen in a case of aluminum phosphide poisoning in India

Introduction: Phosphine poisoning occurs infrequently. As of 1984, 94 cases had been reported in the world literature, with 28 deaths, but its frequency has increased recently. Cases aluminum phosphide were first India 1980. Before then by was unknown. These are mostly suicidal.Material and Method: A 40 year old male resident Phulwari Sharif, Patna, INDIA consumed 3 tablets Aluminum phosphide. The patient referred to AIIMS Patna higher center for treatment where he died at around 7:00 p.m. His body kept overnight Mortuary cold chamber. An autopsy performed INDIA. Chemical analysis report given FSL, came out positive All viscera sent histopathology Department Pathology, India. Spleen electron microscopic examination CDRI, Lucknow, India.Result: spleen congested edematous weighing 140 g; on histopathology, markedly showed focal areas exudation small hemorrhages necrosis. Electron microscopy a cut section that sinusoids dilated congested, splenic mucosa hemorrhagic infarction followed necrosis.Conclusion: histopathological infarction, which is quite possible Celphos poisoning, as it causes widespread organ damage congestion petechial hemorrhages, well organs. Splenic necrosis sequela spleen. Sinusoidal dilatation due edema hypoxic damage002E.